Teenagers who live in vulnerable neighborhoods have a higher probability of entering into a vicious circle where they suffer the consequences of an unfair structure and, at the same time, contribute to the maintenance of it. A research-intervention with photovoice was carried out with youth from a vulnerable multicultural neighborhood on the outskirts of Seville (Spain). The objective was to increase the teenagers’ neighborhood activism through an increase in their psychological sense of community, forecast of future participation, and empowerment. Young girls with different cultural roots, between the ages of 13 and 18 years old participated. After the photographs were taken by the participants, a space was opened for reflection on the strengths and challenges of the neighborhood. The photographs were worked on using artistic techniques to express the desired changes and then the group discussed how to make effective changes. Lastly, the extended community was involved through a photography exhibition. We measured the variables of interest through a pre-post questionnaire given to the participant group and to a comparison group. Complementary, narratives which emerged during the meetings were analyzed. Participants increased their level of psychological sense of community and their wish to participate in the future, but continued with the same level of empowerment. Theoretical contributions and useful suggestions for research-intervention with photovoice are discussed.