Within the post-modern scenario, largely characterized by a sense of diffused social uncertainty and dominated by the ghost of a wide spreading economical and social crisis, social capital, solidarity and social responsibility might represent concrete and efficacious tools to cope with the implications of such cultural drift. The present paper aims at arguing such position by accounting for a repertoire of “good practices” experienced in the south of Italy, which have been read with theoretical and methodological lenses borrowed from social community psychology as well as sociology. The discussion will take into account two case studies (Diffused Guest House and Urban Laboratories) which are both representative in terms of social participation as well as in terms of social capital enhancement. Indeed, all the accounted experiences have shown how the construction of solid and open communities could concretely contribute to enhance social capital as well as to contrast with the diffusion of narrow and conflicting ghetto-communities based on marginality and social uncertainty, which are source for self-segregation, social fragmentation and increasing powerlessness.