Vol. 4 No. 1 (2025): Midwestern Journal of Undergraduate Sciences: Armoring the Immune System

An image of a knight armoring himself for battle.

Exploring the ways the adoptive T Cell therapy spawned one of the world's most powerful techniques in modern immunotherapy: CAR T Cells.

DOI: https://doi.org/10.17161/mjusc.v4i1

Published: 2025-09-22

Full Issue

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From the Editor

Armoring the Immune System Undergraduate Perspectives on the Evolution of CAR T Cell Therapy

J. F. Treml

5
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Reviews

A Double Strike Against Tumor Resistance IL-24 Enhances CAR-T Therapy by Disarming Cancer Stem Cells

Soham Kawade

6-7
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A Humanizing Rewrite for CAR T Cells in Autoimmune Disease: A StepToward Repeatable, Durable Therapy

Samia Chergui

8-9
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FCs and CAR Ts teamwork makes the dreamwork

Yusef Elghzali

10-11
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Striking a Balance scFv affinity modulates expression and activation inCAR T cells

Carson Gray

11-12
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Reprogramming the Enemy Within: Patient-Derived CAR-T Cells Effectively Target Inflammation-Inducing B cells

Isabella Press

13-14
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A Brand New CAR Moving CAR Constructs into Macrophages

Yenny Feng

15-16
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Disparate Biosocial Risk of Malaria andSickle Cell Disease in the United States

Sloane Murphy

17=19
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A CAR T Cell Reading List

Jack Treml

20-26
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The CURE Report

Modeling human phenotypes in the nematode C. elegans during an undergraduate developmental biology course

Sireen Aburaide, Pader Xiong, Daniel Wolfson, Tashi Wangmo, Anthony Vassallo, DJ Smith, Madeline Shaw, Luis Millan, Samantha Meyer, Bobby Lee, Divine Katasi, Evelyn Juen, Allison Hookam, Ahmed Elewa, Yoskar Deleon, Mason Chamberlain, Ahmed Suad, Lian Yaeger

38-47
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Articles

Lipid Peroxidation as a Biomarker for Heavy Metal Stress in Plants

Soham Kawade, Jack Treml, Sonia Thomas, Melissa Daggett, Brendan Mattingly

28-31
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Targeting Streptococcus salivarius in Peri-Implantitis Two Antimicrobial and Antibiofilm Peptides

Samia Chergui, Sonia Thomas, Melissa Daggett, Brendan Mattingly, Jack Treml

32-37
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The Pro-Apoptotic Effects of Curcumin on HCT116 Colorectal Cancer Cells

Kuljeet Kaur, Sonia Thomas, Melissa Daggett, Jack Treml

48-52
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Research Synthesis of Environmental Health Impacts on Mental & Physical Wellness

Robb Morris

54-60
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From the Bench

RuralMed Bringing Medical Opportunities to Rural Students

Arisha Safiq
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The Municipal Farm From Contamination to Conservation: A Plan for the Future

Katelyn Baska, Kathryn Garey
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