Intra-operative Radiation Therapy versus Whole Breast External Beam Radiotherapy: A Comparison of Patient-Reported Outcomes

Authors

  • Jo Leatherman, MS-3 University of Kansas School of Medicine-Wichita
  • Christina Nicholas, M.D.
  • Therese Cusick, M.D.
  • Ellen Cooke, M.D.
  • Elizabeth Ablah, Ph.D.
  • Hayrettin Okut, Ph.D.
  • Diane Hunt, M.D.

DOI:

https://doi.org/10.17161/kjm.vol1415147

Keywords:

breast cancer, intraoperative radiation therapy, external beam radiation therapy, patient-reported outcomes

Abstract

Introduction. This project sought to compare patient-reported outcomes between patients who received intra-operative radiation therapy (IORT) and those who qualified for IORT but received whole-breast external beam radiation therapy (EBRT) following breast-conserving surgery (BCS).

Methods. Three scales from the BREAST-Q Breast Cancer BCT Module Version 2.0 questionnaire were used to collect patient-reported outcomes regarding post-operative physical well-being of the chest, post-operative satisfaction with breast cosmesis and post-operative adverse effects of radiation.

Results. Patients who received EBRT travelled farther on average than patients who received IORT to complete treatment. Respondents who received IORT reported better physical well-being of the chest than those who received EBRT. Regression reveals that the respondent’s age was the determining factor in the difference between IORT and EBRT post-operative physical well-being scores, where younger patients report poorer well-being. There was no difference in patient-reported outcomes regarding post-operative satisfaction with breast cosmesis or adverse effects of radiation.

Conclusions. This study suggests that patients who received IORT report better physical well-being of the chest than patients who received EBRT. There appears to be a relationship between age and physical well-being of chest. This study suggests that there is no difference in patient-reported outcomes concerning post-operative satisfaction with breast cosmesis or post-operative adverse effects of radiation between patients who received IORT and those who received EBRT.

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Published

2021-07-09

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Section

Original Research