Short-Chain Fatty Acids

A Potential Therapy for Colorectal Cancer

Autores/as

  • Samia Chergui University of Kansas
  • Jack Treml University of Kansas

DOI:

https://doi.org/10.17161/mjusc.v3i1.22859

Palabras clave:

colon, cancer, SCFA, microbiome, gut microbiota

Resumen

Short-chain fatty acids (SCFAs), primarily acetate, propionate, and butyrate, have garnered significant attention due to their anti-inflammatory properties within the human body.1 Expanding on these studies, recent research has revealed that SCFAs exhibit selective antitumor effects on colorectal cancer cells (CRC cells). The findings from these investigations have illuminated the influence SCFAs can have on the development and progression of colorectal cancer. These discoveries underscore the therapeutic potential SCFAs might offer in the management and treatment of colorectal cancer.

Referencias

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Li, Q., Ding, C., Meng, T., Lu, W., Liu, W., Hao, H., & Cao, L. (2017). Butyrate suppresses the motility of colorectal cancer cells via deactivating Akt/ERK signaling in histone deacetylase dependent manner. Journal of Pharmacological Sciences, 135(4), 148–155. https://doi.org/10.1016/j. jphs.2017.11.004

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Publicado

2024-09-17

Cómo citar

Chergui, S., & Treml, J. (2024). Short-Chain Fatty Acids: A Potential Therapy for Colorectal Cancer. Midwestern Journal of Undergraduate Sciences, 3(1), 9-10. https://doi.org/10.17161/mjusc.v3i1.22859