TIGIT: A Novel Entry in NK Cell Regulation

Autores/as

  • Sophia Khatri University of Kansas, School of Professional Studies, Biotechnology

DOI:

https://doi.org/10.17161/mjusc.v1i1.18571

Palabras clave:

TIGIT, checkpoint inhibitor, immunity, NK Cell

Resumen

While TIGIT’s immunoregulatory role in T Cells has been described, the mechanisms through which TIGIT modulates NK Cell activity has remained elusive. Recent research by Staniesky et al. reveals that the expression of TIGIT by NK cells inhibits the lysis of PVR and PVRL1-expressing target cells in an ITIM-dependent manner.

Cover of issue 1 of the Midwestern Journal of Undergraduate Sciences showing an illustration of checkpoint inhibitors

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Publicado

2022-10-03

Número

Vol. 1 Núm. 1 (2022)

Sección

Reviews

Licencia

Creative Commons License

Esta obra está bajo una licencia internacional Creative Commons Atribución-NoComercial 4.0.

© The Author(s)

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International license. 

Cómo citar

Khatri, S. (2022). TIGIT: A Novel Entry in NK Cell Regulation. Midwestern Journal of Undergraduate Sciences, 1(1), 6. https://doi.org/10.17161/mjusc.v1i1.18571