TIGIT: A Novel Entry in NK Cell Regulation

Auteurs

  • Sophia Khatri University of Kansas, School of Professional Studies, Biotechnology

DOI :

https://doi.org/10.17161/mjusc.v1i1.18571

Mots-clés :

TIGIT, checkpoint inhibitor, immunity, NK Cell

Résumé

While TIGIT’s immunoregulatory role in T Cells has been described, the mechanisms through which TIGIT modulates NK Cell activity has remained elusive. Recent research by Staniesky et al. reveals that the expression of TIGIT by NK cells inhibits the lysis of PVR and PVRL1-expressing target cells in an ITIM-dependent manner.

Cover of issue 1 of the Midwestern Journal of Undergraduate Sciences showing an illustration of checkpoint inhibitors

Téléchargements

Publiée

2022-10-03

Numéro

Vol. 1 No 1 (2022)

Rubrique

Reviews

Licence

Creative Commons License

Ce travail est disponible sous licence Creative Commons Attribution - Pas d’Utilisation Commerciale 4.0 International.

© The Author(s)

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International license. 

Comment citer

Khatri, S. (2022). TIGIT: A Novel Entry in NK Cell Regulation. Midwestern Journal of Undergraduate Sciences, 1(1), 6. https://doi.org/10.17161/mjusc.v1i1.18571