TIGIT: A Novel Entry in NK Cell Regulation

Authors

  • Sophia Khatri University of Kansas, School of Professional Studies, Biotechnology

DOI:

https://doi.org/10.17161/mjusc.v1i1.18571

Keywords:

TIGIT, checkpoint inhibitor, immunity, NK Cell

Abstract

While TIGIT’s immunoregulatory role in T Cells has been described, the mechanisms through which TIGIT modulates NK Cell activity has remained elusive. Recent research by Staniesky et al. reveals that the expression of TIGIT by NK cells inhibits the lysis of PVR and PVRL1-expressing target cells in an ITIM-dependent manner.

Cover of issue 1 of the Midwestern Journal of Undergraduate Sciences showing an illustration of checkpoint inhibitors

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Published

2022-10-03

Issue

Vol. 1 No. 1 (2022)

Section

Reviews

License

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

© The Author(s)

This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International license. 

How to Cite

Khatri, S. (2022). TIGIT: A Novel Entry in NK Cell Regulation. Midwestern Journal of Undergraduate Sciences, 1(1), 6. https://doi.org/10.17161/mjusc.v1i1.18571