Long standing DADS preceding AL amyloidosis: A sentinel event or serendipitous association?

Authors

  • Deepak Menon MD Toronto General Hospital
  • Sara Alnajjar MD Toronto General Hospital
  • Vera Bril MD FRCP(C) Toronto General Hospital

DOI:

https://doi.org/10.17161/rrnmf.v2i3.15091

Keywords:

chronic inflammatory demyelinating polyneuropathy, distal acquired demyelinating symmetric neuropathy,, monoclonal gammopathy of unknown significance, amyloidosis, free light chain assay

Metrics

Metrics Loading ...

Downloads

Download data is not yet available.

References

Vaxman I, Gertz M. When to Suspect a Diagnosis of Amyloidosis. AHA 2020;143:304–11. https://doi.org/10.1159/000506617.

Karam C, Moshe-Lilie O, Chahin N, Ragole T, Medvedova E, Silbermann R. Diagnosis of paraproteinemic neuropathy: Room for improvement. J Neurol Sci 2020;415:116902. https://doi.org/10.1016/j.jns.2020.116902.

Katz JS, Saperstein DS, Gronseth G, Amato AA, Barohn RJ. Distal acquired demyelinating symmetric neuropathy. Neurology 2000;54:615–20. https://doi.org/10.1212/wnl.54.3.615.

Joint Task Force of the EFNS and the PNS. European Federation of Neurological Societies/Peripheral Nerve Society Guideline on management of paraproteinemic demyelinating neuropathies. Report of a Joint Task Force of the European Federation of Neurological Societies and the Peripheral Nerve Society--first revision. J Peripher Nerv Syst 2010;15:185–95. https://doi.org/10.1111/j.1529-8027.2010.00278.x.

Gertz MA. Immunoglobulin light chain amyloidosis: 2020 update on diagnosis, prognosis, and treatment. Am J Hematol 2020;95:848–60. https://doi.org/10.1002/ajh.25819.

Zingone A, Kuehl WM. Pathogenesis of Monoclonal Gammopathy of Undetermined Significance (MGUS) and Progression to Multiple Myeloma. Semin Hematol 2011;48:4–12. https://doi.org/10.1053/j.seminhematol.2010.11.003.

Merlini G, Palladini G. Differential diagnosis of monoclonal gammopathy of undetermined significance. Hematology 2012;2012:595–603. https://doi.org/10.1182/asheducation.V2012.1.595.3798563.

Duston MA, Skinner M, Anderson J, Cohen AS. Peripheral neuropathy as an early marker of AL amyloidosis. Arch Intern Med 1989;149:358–60.

Kaku M, Berk JL. Neuropathy Associated with Systemic Amyloidosis. Semin Neurol 2019;39:578–88. https://doi.org/10.1055/s-0039-1688994.

Rajkumar SV, Gertz MA, Kyle RA. Prognosis of patients with primary systemic amyloidosis who present with dominant neuropathy. Am J Med 1998;104:232–7. https://doi.org/10.1016/s0002-9343(98)00037-0.

Matsuda M, Gono T, Morita H, Katoh N, Kodaira M, Ikeda S. Peripheral nerve involvement in primary systemic AL amyloidosis: a clinical and electrophysiological study. Eur J Neurol 2011;18:604–10. https://doi.org/10.1111/j.1468-1331.2010.03215.x.

Traynor AE, Gertz MA, Kyle RA. Cranial neuropathy associated with primary amyloidosis. Ann Neurol 1991;29:451–4. https://doi.org/10.1002/ana.410290421.

Adams D, Lozeron P, Theaudin M, Denier C, Fagniez O, Rerat K, et al. Varied patterns of inaugural light-chain (AL) amyloid polyneuropathy: a monocentric study of 24 patients. Amyloid 2011;18:98–100. https://doi.org/10.3109/13506129.2011.574354036.

Cheng RR, Eskandari R, Welsh CT, Varma AK. A case of isolated amyloid light-chain amyloidosis of the radial nerve. J Neurosurg 2016;125:598–602. https://doi.org/10.3171/2015.10.JNS151095.

Mathis S, Magy L, Diallo L, Boukhris S, Vallat J-M. Amyloid neuropathy mimicking chronic inflammatory demyelinating polyneuropathy. Muscle Nerve 2012;45:26–31. https://doi.org/10.1002/mus.22229.

Li J, Li Y, Chen H, Xing S, Feng H, Liu D, et al. Autonomic Neuropathy and Albuminocytologic Dissociation in Cerebrospinal Fluid As the Presenting Features of Primary Amyloidosis: A Case Report. Front Neurol 2017;8. https://doi.org/10.3389/fneur.2017.00368.

Chaudhry HM, Mauermann ML, Rajkumar SV. Monoclonal Gammopathy Associated Peripheral Neuropathy: Diagnosis and Management. Mayo Clin Proc 2017;92:838–50. https://doi.org/10.1016/j.mayocp.2017.02.003.

Gertz MA. Immunoglobulin light chain amyloidosis diagnosis and treatment algorithm 2018. Blood Cancer Journal 2018;8:1–8. https://doi.org/10.1038/s41408-018-0080-9.

Dispenzieri A, Kyle R, Merlini G, Miguel JS, Ludwig H, Hajek R, et al. International Myeloma Working Group guidelines for serum-free light chain analysis in multiple myeloma and related disorders. Leukemia 2009;23:215–24. https://doi.org/10.1038/leu.2008.307.

Kyle RA, Durie BGM, Rajkumar SV, Landgren O, Blade J, Merlini G, et al. Monoclonal gammopathy of undetermined significance (MGUS) and smoldering (asymptomatic) multiple myeloma: IMWG consensus perspectives risk factors for progression and guidelines for monitoring and management. Leukemia 2010;24:1121–7. https://doi.org/10.1038/leu.2010.60.

Rögnvaldsson S, Turesson I, Björkholm M, Landgren O, Kristinsson SY. Peripheral Neuropathy in MGUS and Progression to Amyloid Light-Chain Amyloidosis: A Population-Based Study Including 15,351 MGUS Cases. Blood 2019;134:5444–5444. https://doi.org/10.1182/blood-2019-131514.

Enqvist S, Mellqvist U-H, Mölne J, Sletten K, Murphy C, Solomon A, et al. A father and his son with systemic AL amyloidosis. Haematologica 2009;94:437–9. https://doi.org/10.3324/haematol.13640.

Downloads

Published

2021-08-03

Issue

Section

Clinic and Case Reports

How to Cite

Menon, D., Alnajjar, S., & Bril, V. (2021). Long standing DADS preceding AL amyloidosis: A sentinel event or serendipitous association?. RRNMF Neuromuscular Journal, 2(3), 41-45. https://doi.org/10.17161/rrnmf.v2i3.15091