Unusual neurological presentations resulting in diagnosis of lymphoma in three patients

neurological presentation of lymphoma

Authors

  • Yuebing Li MD PhD Li
  • Zachary McKee MD

DOI:

https://doi.org/10.17161/rrnmf.v3i3.17930

Keywords:

lymphoma, polyradiculoneuropathy, encephalitis, frontal lobe dysfunction, PET

Abstract

Nervous system involvement affects up to one-third of patients with lymphoma, via a variety of mechanisms ranging from direct invasion, to demyelination, paraneoplastic processes, and treatment related complications. Nervous system involvement can manifest at any location and occur at any stage of lymphoma, often resulting in distinct and atypical patterns. Here we describe three patients, presenting each with motor predominant polyradiculoneuropathy and cranial neuropathy, transient encephalitis, and frontal gait dysfunction. Through further workup, all were diagnosed with lymphoma, with their neurological manifestations directly or indirectly related to the underlying lymphoma. Our study serves as an alert that in patients presenting with unusual neurological symptoms, lymphoma should be a consideration on the differential diagnosis. 

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References

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Published

2022-09-26

How to Cite

Li, Y., & McKee, Z. (2022). Unusual neurological presentations resulting in diagnosis of lymphoma in three patients : neurological presentation of lymphoma. RRNMF Neuromuscular Journal, 3(3), 25–28. https://doi.org/10.17161/rrnmf.v3i3.17930

Issue

Section

Clinic Stuff (Case Reports)