Cryptococcal Meningitis in an Immunocompetent Male: Case Report

72-year-old immunocompetent male with the unexpected finding of cryptococcal meningitis following recent motor vehicle accident

Authors

DOI:

https://doi.org/10.17161/rrnmf.v4i2.18989

Keywords:

cryptococcal meningitis, meningitis, cryptococcus, infection, trauma

Abstract

Cryptococcal meningitis is a life-threatening condition caused by an invasive, opportunistic, encapsulated saprophytic fungus, either Cryptococcus neoformans or Cryptococcus gattii most often in immunocompromised patients, especially those with human immunodeficiency virus (HIV). Overwhelming invasive infection of immunocompetent patients is rather uncommon, and diagnosis is often challenging due to a more indolent course. We present a case of cryptococcal meningitis (CM) in a 72-year-old immunocompetent male following a recent motor vehicle accident.

Metrics

Metrics Loading ...

Downloads

Download data is not yet available.

References

Kozubowski L, Heitman J. Profiling a killer, the development of Cryptococcus neoformans. FEMS Microbiol Rev. 2012 Jan;36(1):78-94. doi: 10.1111/j.1574-6976.2011.00286.x. Epub 2011 Jul 4. PMID: 21658085; PMCID: PMC3318972.

Shokouhi S, Hakamifard A. Meningitis Caused by Cryptococcus neoformans in an Apparently Immunocompetent Patient. J Investig Med High Impact Case Rep. 2022 Jan-Dec;10:23247096221111779. doi: 10.1177/23247096221111779. PMID: 35848079; PMCID: PMC9290167.

Mwaba P, Mwansa J, Chintu C, et al. Clinical presentation, natural history, and cumulative death rates of 230 adults with primary cryptococcal meningitis in Zambian AIDS patients treated under local conditions. Postgrad Med J. 2001;77(914):769-773.

Brizendine KD, Baddley JW, Pappas PG. Predictors of mortality and differences in clinical features among patients with Cryptococcosis according to immune status. PLoS One. 2013;8(3):e60431. doi: 10.1371/journal.pone.0060431. Epub 2013 Mar 26. PMID: 23555970; PMCID: PMC3608592.

Henao-Martínez AF, Gross L, Mcnair B, McCollister B, DeSanto K, Montoya JG, Shapiro L, Beckham JD. Risk Factors for Cryptococcal Meningitis: A Single United States Center Experience. Mycopathologia. 2016 Dec;181(11-12):807-814. doi: 10.1007/s11046-016-0048-x. Epub 2016 Aug 8. PMID: 27502502; PMCID: PMC5121069.

Poley M, Koubek R, Walsh L, McGillen B. Cryptococcal meningitis in an apparent immunocompetent patient. J Investig Med High Impact Case Rep. 2019;7:2324709619834578.

Garcia-Villa M, Gonzalez-Lara A, Rodriguez-Leyva I. Cryptococcal meningitis due to Cryptococcus gattii in an immunocompetent patient: uncommon presentation of a thunderclap headache. BMJ Case Rep. 2022 Apr 4;15(4):e246158. doi: 10.1136/bcr-2021-246158. PMID: 35379676; PMCID: PMC8981403.

Jelaun Newsome, MC USA, Dana Nguyen, MC USA, Cryptococcal Meningitis Caused by Cryptococcus neoformans in an Immunocompetent Soldier, Military Medicine, Volume 179, Issue 9, September 2014, Pages e1059–e1061, https://doi.org/10.7205/MILMED-D-14-00020

Downloads

Published

2023-06-19

Issue

Section

Clinic and Case Reports

How to Cite

Scott, K., Smith, C., Walker, D., & Fender, B. (2023). Cryptococcal Meningitis in an Immunocompetent Male: Case Report: 72-year-old immunocompetent male with the unexpected finding of cryptococcal meningitis following recent motor vehicle accident. RRNMF Neuromuscular Journal, 4(2), 7-9. https://doi.org/10.17161/rrnmf.v4i2.18989