A rare case report of neurolymphomatosis with NK-T-cell lymphoma





neurolymphomatosis, T-cell lymphoma, role of nerve biopsy, non-hodgkin's lymphoma, MRI Neurography


Neurolymphomatosis (NL) is a rare entity. It is usually a manifestation of B-cell lymphoma. Here we describe a case of neurolymphomatosis in a 72 year old man who was in remission for Nasal T-cell lymphoma and presented to us with subacute onset painful mononeuritis like weakness involving all 4 limbs sequentially over a period of 4 months. he was initially treated as CIDP with steroids but later in view of progression he was evaluated further. His FDG PET-CT showed increased uptake in left brachial plexus which was confirmed by subsequent MRI neurography. He underwent biopsy of left brachial plexus and diagnosis of neurolymphomatosis was confirmed. He was treated with intravenous immunoglobulins (2 gm/kg) over 5 days with minimal improvement in his neurological symptoms, his shoulder pain improved and he could feed himself with right hand. He was offered palliative treatment in view of poor prognosis seen in neurolymphomatosis. He succumbed to the illness 3 months later.


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Author Biographies

  • Ruta R. Savaj MD, P.D. Hinduja hospital, Mumbai

    MD Medicine, Resident in department of neurology

  • Megha S Uppin MD FICP, Nizam's institute of medical sciences

    Additional Professor, Department of pathology

    MD, FICP

  • Megha Dhamne MD, P. D. Hinduja Hospital and Medical Research Center

    Consultant Neurology, P. D. Hinduja Hospital and Medical Research Center.

    MD Neurology


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Clinic and Case Reports

How to Cite

Savaj, R., Harke Uppin, M., & Dhamne, M. (2023). A rare case report of neurolymphomatosis with NK-T-cell lymphoma. RRNMF Neuromuscular Journal, 4(4). https://doi.org/10.17161/rrnmf.v4i4.20277