Bilateral Ptosis and Limb Myokymia: Regional Variant of Guillain-Barré Syndrome?

Biltateral ptosis and limb myokymia in Guillain-Barré Syndrome?

  • Felix Cheng Dept. of Neurology, Jacobs School of Medicine and Biomedical Sciences, Univ. at Buffalo/SUNY
  • Gil Wolfe Dept. of Neurology, Univ. at Buffalo/SUNY
  • Richard Barohn Dept. of Neurology, University of Missouri School of Medicine
  • Jonathan Katz
Keywords: Guillain-Barré syndrome, ptosis, antiganglioside antibodies, myokymia

Abstract

Isolated bilateral ptosis as an initial sign of  Guillain-Barré Syndrome (GBS) with subsequent limb paralysis or paresis has been reported.  However, to our knowledge, bilateral ptosis with subsequent limb myokymia but without ophthalmoplegia, facial or extremity weakness has not been observed.  Our patient developed severe bilateral ptosis over several days. There was no facial or extremity weakness although limb myokymia was seen.  Laboratory studies excluded common causes of ptosis and were suggestive of GBS. We believe our patient extends the clinical spectrum of GBS, and that binocular ptosis represents a mild regional variant of this neuropathy.

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Published
2020-06-09
How to Cite
Cheng, F., Wolfe, G., Barohn, R., & Katz, J. (2020). Bilateral Ptosis and Limb Myokymia: Regional Variant of Guillain-Barré Syndrome? Biltateral ptosis and limb myokymia in Guillain-Barré Syndrome?. RRNMF Neuromuscular Journal, 1(2), 22-24. Retrieved from https://journals.ku.edu/rrnmf/article/view/13579
Section
Clinic Stuff (Case Reports)